Is Fasting The Missing Key To Longevity?
Updated: Apr 1, 2020

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Autophagy is a buzz word these days. For those of you that somehow have missed the đşđˇđˇ on it; đŞđľâđ´ đŚđ´đ´đŚđŻđľđŞđ˘đđđş đľđŠđŚ đ¤đđŚđ˘đŻđŚđł đ°đ§ đşđ°đśđł đŁđ°đĽđş, degrading damaged and dysfunctional cells and protein structures before they cause problems in the body. âŁ
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Many individuals promote it as being the đ´đ˘đˇđŞđŻđ¨ đ¨đłđ˘đ¤đŚ đ°đ§ đŠđŚđ˘đđľđŠ and recommend prolonged fasting to maximize its up-regulation, but that isnât necessary.âŁ
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Autophagy is always going on due to its necessity for cleaning up and the #đ thing that stimulates it is a cellular energy deficit. âŁ
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Regardless of any other factors, such as nutrient signaling from amino acids, or growth factor signaling from hormones like insulin â an energy deficit within the cell prevails and promotes the activation of the autophagy regulator, AMPK, which sits on a see-saw with the master regulator of growth and reproduction, mTOR.âŁ
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Ideally, we want to balance our đ˝đ˛đżđśđźđąđ đźđł đłđŽđđđśđťđ´ đđśđđľ đ˝đ˛đżđśđźđąđ đźđł đłđ˛đŽđđđśđťđ´, so that we get the best of both mTOR and AMPK. Itâs sufficient to fast for 12-16 hours every night as we sleep, depending on your goals, and then eat within the remaining time so that you can spend some time growing and building new tissue, then cleaning up any dysfunctional proteins that come about during that growth period.âŁ
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đđłđ°đđ°đŻđ¨đŚđĽ đ§đ˘đ´đľđŞđŻđ¨ đđŚđ˘đĽđ´ đľđ° đŚđšđ¤đŚđ´đ´đŞđˇđŚ đ˘đŻđĽ đśđŻđŻđŚđ¤đŚđ´đ´đ˘đłđş đŽđśđ´đ¤đđŚ đđ°đ´đ´. Itâs fine if you are very obese, but itâs not ideal, and it is certainly not beneficial to anyone who is already at a healthy body weight.
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